Search | Result
| ID | 4324 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Skin |
| Sample | Tissue |
| Disease type | Melanoma |
| Cell type | T cells |
| Cell type (subtype) | Activated cytotoxic T-cell lymphocyte |
| Cell marker | CD8, GZMA, PRF1 |
| Frequency | |
| PubMed ID | 32296058 |
| Journal | Nat Commun |
| SCI IF | 12.121 |
| Evidence | Marker gene expression levels across TIL clusters. Relative expression of key marker genes associated with a cytotoxic T-cell phenotype (CD8, GZMA, and PRF1), CD4 phenotype (CD4 and IL7R), and a multiply checkpoint-inhibited phenotype (FOXP3, CTLA-4, GITR, and ICOS) are overlaid on the tSNE clusters |
| Title | Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma |
| Authors | Akash Mitra et al. |
| Date | 2020.4 |
| Data available | GSE78220, SE91061 |
