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ID 4305
Class Mammalia
Species Homo sapiens
Tissue Skin
Sample Tissue
Disease type Healthy female donors
Cell type T cells
Cell type (subtype) T cells
Cell marker PTPRC
Frequency
PubMed ID 31930613
Journal FASEB J
SCI IF 4.966
Evidence After t-SNE-clustering based on principal component analysis, we were able to discriminate between 18 different cell populations in the Human skin, including T-cells (TC), dendritic cells (DC), macrophages (Mac), Langerhans cells (LC), mast cells (MC), Endothelial cellss (EC), lymphatic EC (LEC), pericytes (PC), smooth muscle cells (SMC), four distinct keratinocyte (KC), and six different FB populations (Figure 1A). All clusters were confirmed by visualization of marker gene expressions (Figure 1B)
Title Deciphering the functional heterogeneity of skin fibroblasts using single-cell RNA sequencing.
Authors Vorstandlechner V et al.
Date 2020.3
Data available NA