Search | Result
ID | 2325 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Gut |
Sample | Organoids |
Disease type | Childhood Crohn's Disease |
Cell type | Epithelial cells |
Cell type (subtype) | Epithelial cells 1 |
Cell marker | EPCAM, LGR5, ASCL2, EPHB2, RGMB |
Frequency | |
PubMed ID | 33290721 |
Journal | Dev Cell |
SCI IF | 10.092 |
Evidence | Among them were two clusters: a cluster with high expression of canonical adult-stem-cell genes, including leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), achaete-scute complex homolog 2 (ASCL2), ephrin type-B receptor 2 (EPHB2), and repulsive guidance molecule BMP co-receptor B (RGMB) |
Title | Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn Disease |
Authors | Rasa Elmentaite et al. |
Date | 2020.12 |
Data available | NA |