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ID 4068
Class Mammalia
Species Homo sapiens
Tissue Skin
Sample Cell line
Disease type NA
Cell type NA
Cell type (subtype) AXL NRG1 doubly positive cells
Cell marker AXL, JUN, NGFR, WNT5A, FGFR1, NRG1
Frequency
PubMed ID 30061114
Journal Genome Res
SCI IF 11.093
Evidence parental cells, resistant cells, and a new population of cells that sat at the interface between these two major clusters (marked in yellow on Fig. 5A and triangles in Supplemental Fig. S9A-F). The cells in this yellow intermediate population were marked by high levels of AXL, JUN, NGFR, WNT5A, FGFR1 and NRG1 (Supplemental Fig. S8, S9),
Title Single-cell RNA-seq analysis identifies markers of resistance to targeted BRAF inhibitors in melanoma cell populations
Authors Yu-Jui Ho et al.
Date 2018.9
Data available SRP127328