Evidence |
Fibroblasts highly expressed classical markers of ENG, COL1A2, and ACTA2 (Additional file 2 Figure S10b), while the remaining two clusters were composed of epithelial cells, characterized by the high expression of the Epithelial Cell Adhesion Molecule (EPCAM). Notably, one of the two clusters was characterized by specific expression of cell cycle-related genes including MKI67 and CDK1, as well as cancer-associated genes including S100A14, MUC13, and KRT7, and thus was defined as malignant cells |