Search | Result
| ID | 4598 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Tibial articular cartilages |
| Sample | Tissue |
| Disease type | Osteoarthritis |
| Cell type | Immune cells |
| Cell type (subtype) | Immune cells |
| Cell marker | PTPRC, HLA-DRA |
| Frequency | |
| PubMed ID | 32616761 |
| Journal | Sci Rep |
| SCI IF | 3.992 |
| Evidence | Proliferating immune cells (ProIC) in cluster 14, expressing genes related to immune cell markers (HLA-DRA and PTPRC), were also characterized by high differential expression of genes responsible for regulation of cell division, the cell cycle, chromatin structure regulation and apoptosis inhibition (namely CENPF, CDK1, HIST1H4C and BIRC5). |
| Title | Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis |
| Authors | Ching-Heng Chou et al. |
| Date | 2020.7 |
| Data available | GSE152805 |
