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ID 7660
Class Mammalia
Species Mouse
Tissue Melanoma
Sample Tissue
Disease type Melanoma
Cell type Neural cells
Cell type (subtype) Neural crest cells
Cell marker Foxd3, L1cam
Frequency
PubMed ID 31685822
Journal Nat Commun
SCI IF 12.121
Evidence Immunohistochemical examination of 10 distinct tumors showed that in most of the tumors, Tomato+ tumor cells express melanocytic markers Dct and MITF, neuronal markers Nestin, Tubb3 and Gfap, mesenchymal marker Pdgfra and proliferation marker Ki67
Title A novel Mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling Human disease.
Authors Qi Sun, Wendy Lee. et al.
Date 2019.11
Data available GSE113502