Search | Result
| ID | 4087 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Skin |
| Sample | Tissue |
| Disease type | Normal |
| Cell type | Secretory cells |
| Cell type (subtype) | Secretory reticular |
| Cell marker | WISP2, SLPI, MFAP5, TSPAN8 |
| Frequency | |
| PubMed ID | 33385399 |
| Journal | J Invest Dermatol |
| SCI IF | 7.143 |
| Evidence | In a study on dermal aging, Sole_-Boldo et al. (2020) determined four main young fibroblast subpopulations that could be discriminated into five after secondary analysis: (i) secretory reticular (WISP2, SLPI, MFAP5, TSPAN8), (ii) secretory papillary (APCDD1, ID1, WIF1, COL18A1, PTDGS), (iii) mesenchymal (ASPN, POSTN, GPC3, TNN, SFRP1), and (iv) proinflammatory (CCL19, APOE, CXCL2, CXCL3, EFEMP1), which in turn was composed of two sub clusters. |
| Title | Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing Studies |
| Authors | Alex M Ascension et al. |
| Date | 2020.12 |
| Data available | GSE130973 |
