Search | Result
| ID | 3822 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Pancreas |
| Sample | Organoids |
| Disease type | NA |
| Cell type | Beta cells |
| Cell type (subtype) | Beta cells |
| Cell marker | PDX1, NKX6-1, NEUROD1, RFX6, GCK, ISL1, SYT4 |
| Frequency | |
| PubMed ID | 32814902 |
| Journal | Nature |
| SCI IF | 49.962 |
| Evidence | Comparative transcriptional analyses confirmed similar expression of multiple key islet cell markers in WNT4-treated HILOs (wHILOs) and Human islets, including beta-cell-specific (NKX6-1, NEUROD1, RFX6, GCK, ISL1, SYT4 and PDX1) and alpha-cell specific (ARX) genes |
| Title | Immune-evasive Human islet-like organoids ameliorate diabetes |
| Authors | Eiji Yoshihara et al. |
| Date | 2020.1 |
| Data available | PRJNA505532 |
