Search | Result
| ID | 3938 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Prostate |
| Sample | Tissue |
| Disease type | Benign prostatic hyperplasia |
| Cell type | Myofibroblasts |
| Cell type (subtype) | Myofibroblasts |
| Cell marker | BMP5, CXCL13 |
| Frequency | |
| PubMed ID | 31094703 |
| Journal | JCI Insight |
| SCI IF | 6.205 |
| Evidence | Figure 5.scRNA-Seq reveals altered cell subsets in BPH.(A) Two-dimensional projection (t-SNE plot) of single-cell transcriptomes stratifies prostate tissue cells (dots) into distinct clusters, identifiable by characteristic expression of marker genes, including (B) KRT13 (basal epithelium) (red intensity scales to maximum log2 expression), (C) KLK3 (secretory epithelium), and (D) DCN (fibroblasts). Additional cell type markers are shown in Supplemental Figure 6 |
| Title | Genomic analysis of benign prostatic hyperplasia implicates cellular re-landscaping in disease pathogenesis |
| Authors | Lance W Middleton et al. |
| Date | 2019.5 |
| Data available | All RNA-Seq and WES data are available from the database of Genotypes and Phenotypes (phs001698.v1.p1). |
