| Evidence |
Supplemental Figure S6. Single-cell RNAseq; visualization of additional markers.(A) Two-dimensional projection (t-SNE plot) of single cell transcriptomes stratifies prostate tissue cells (dots) into distinct clusters, identifiable by characteristic expression of marker genes, including (B) KRT18 (all epithelium) (red intensity scales to maximum log2 expression), (C) PTPRC (CD45 antigen; leukocytes), and (D) VWF (Von Willebrand Factor; endothelium). (E) Normal prostate tissue cell subset, illustrating expression of (F) ESR1 (within fibroblasts). (G) BPH tissue cell subset, illustrating expression of (H) ESR1 (within fibroblasts). Insets magnify select cell clusters |
