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ID 3847
Class Mammalia
Species Homo sapiens
Tissue Pancreas
Sample Organoids
Disease type NA
Cell type Islet cells
Cell type (subtype) Islet alpha cells
Cell marker ARX
Frequency
PubMed ID 32814902
Journal Nature
SCI IF 49.962
Evidence Comparative transcriptional analyses confirmed similar expression of multiple key islet cell markers in WNT4-treated HILOs (wHILOs) and Human islets, including beta-cell-specific (NKX6-1, NEUROD1, RFX6, GCK, ISL1, SYT4 and PDX1) and alpha-cell specific (ARX) genes
Title Immune-evasive Human islet-like organoids ameliorate diabetes
Authors Eiji Yoshihara et al.
Date 2020.1
Data available PRJNA505532