Search | Result
ID | 3754 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Nose |
Sample | Tissue |
Disease type | Aspirin-exacerbated respiratory disease, chronic rhinosinusitis with nasal polyps |
Cell type | Myeloid cells |
Cell type (subtype) | Myeloid cells |
Cell marker | HLA-DRA, CYSLTR2 |
Frequency | |
PubMed ID | 32371071 |
Journal | J ALLERGY CLIN IMMUNOL |
SCI IF | 10.228 |
Evidence | leukotriene receptors CysLTR-2 (CYSLTR2) and CysLTR-3 (OXGR1) were most prominent in myeloid cells and glandular epithelial cells, respectively.Clusters were annotated on the basis of expression of the following canonic genes KRT5 (basal epithelial cells), KRT8 (apical epithelial cells), LTF (glandular epithelial cells), FOXJ1 (ciliated epithelial cells), COL1A2 (fibroblasts), ACKR1 (Endothelial cellss), CD79A (B cells), TRBC2 (T cells), HLA-DRA (myeloid), and TPSAB1 (mast cells) |
Title | Activation of the 15-lipoxygenase pathway in aspirin-exacerbated respiratory disease |
Authors | Whitney W. Stevens et al. |
Date | 2020 |
Data available | NA |