Search | Result
ID | 3106 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Lung |
Sample | Tissue |
Disease type | Lymphangioleiomyomatosis |
Cell type | Alveolar cells |
Cell type (subtype) | Differentiated smooth muscle cells |
Cell marker | PDGFRa, DCN, SFRP4, MYLK, MYL9, DES |
Frequency | |
PubMed ID | 33159078 |
Journal | Nat Commun |
SCI IF | 12.121 |
Evidence | In control lung, the alveolar epithelial cell (AEC)niche was divided into two canonical clusters: alveolar type 2(AT2), marked by the high differential expression of SFTPC, SFTPD, and SFTPA genes, and alveolar type-1 (AT1) cells, characterized by HOPX, AGER, and AQP4 gene expression |
Title | mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline. |
Authors | Obraztsova K et al. |
Date | 2020.11 |
Data available | GSE139819 |