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ID 3110
Class Mammalia
Species Homo sapiens
Tissue Lung
Sample Tissue
Disease type Lung adenocarcinomas
Cell type Myeloid cells
Cell type (subtype) Myeloid-derived suppressor cells (mdsc)
Cell marker CSF1R, ITGAX, IL10
Frequency
PubMed ID 32042191
Journal Nat Med
SCI IF 36.13
Evidence A subset of ITGAM(CD11B)+ immature myeloid cells expressing both CSF1R and immunosuppressive IL10 were further distinguished as myeloid-derived suppressor cells (MDSCs), which have been shown to dampen inflammatory responses
Title Regenerative lineages and immune-mediated pruning in lung cancer metastasis
Authors Ashley M Laughney et al.
Date 2020.2
Data available GSE123920