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ID 1107
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample Cell line
Disease type NA
Cell type Endothelial cells
Cell type (subtype) Liver sinusoidal endothelial cells (LSECs)
Cell marker LYVE1, CD36, CD14, STAB2, MRC1, FCGR2B, CD54, STAB1, CLEC1B, FVIII, GATA4
Frequency
PubMed ID 32640183
Journal Cell Stem Cell
SCI IF 20.86
Evidence The sinusoids are lined with unique Endothelial cellss known as liver sinusoidal Endothelial cellss (LSECs) that are distinguished from other Endothelial cellss by their reduced levels of expression of CD34, CD31 (PECAM1), and von Willebrand factor (VWF) and elevated expression of LYVE1, CD14, CD32B (FCGR2B), CD36, CD54, STAB1, STAB2, CLEC1B, and factor VIII (FVIII) (F8) / Figure 6 (B) Candidate expression patterns of markers of LSECs (PECAM1, FCGR2B, LYVE1, STAB2, F8, CD14, MRC1, and GATA4), general vasculature (PECAM1 and VWF), and mesenchyme/fibroblasts (PDGFRB).
Title Generation of Functional Liver Sinusoidal Endothelial cellss from Human Pluripotent Stem-Cell- Derived Venous Angioblasts
Authors Gage et al.
Date 2020.8
Data available NA