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ID 3467
Class Mammalia
Species Homo sapiens
Tissue Lung
Sample Tissue
Disease type Normal
Cell type Epithelial cells
Cell type (subtype) Epithelial cells
Cell marker KRT18, MSLN
Frequency
PubMed ID 33159078
Journal Nat Commun
SCI IF 12.121
Evidence In control lung, the alveolar epithelial cell (AEC)niche was divided into two canonical clusters: alveolar type 2(AT2), marked by the high differential expression of SFTPC, SFTPD, and SFTPA genes, and alveolar type-1 (AT1) cells, characterized by HOPX, AGER, and AQP4 gene expression
Title mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline.
Authors Obraztsova K et al.
Date 2020.11
Data available GSE139819