Search | Result
ID | 4030 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Retina |
Sample | Tissue |
Disease type | NA |
Cell type | Astrocytes |
Cell type (subtype) | Astrocytes |
Cell marker | GFAP, IFITM3, SOCS3, SLPI, CH25H |
Frequency | |
PubMed ID | 32069977 |
Journal | Cells |
SCI IF | 4.366 |
Evidence | Cells in this cluster demonstrated high expression of the glial fibrillary acid protein (GFAP), which is widely expressed in astrocytes responding to neuronal injury [20], and the astrocyte-specific infammatory cytokine IFITM3 [21]. Astrocytes from the AIR donor were enriched for SOCS3 [22], SLPI [23], and CH25H [24], genes that have all been previously found to be expressed in astrocytes responding to CNS injury. |
Title | Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations |
Authors | Andrew P Voigt et al. |
Date | 2020.2 |
Data available | GSE142449 |