Search | Result

ID 4030
Class Mammalia
Species Homo sapiens
Tissue Retina
Sample Tissue
Disease type NA
Cell type Astrocytes
Cell type (subtype) Astrocytes
Cell marker GFAP, IFITM3, SOCS3, SLPI, CH25H
Frequency
PubMed ID 32069977
Journal Cells
SCI IF 4.366
Evidence Cells in this cluster demonstrated high expression of the glial fibrillary acid protein (GFAP), which is widely expressed in astrocytes responding to neuronal injury [20], and the astrocyte-specific infammatory cytokine IFITM3 [21]. Astrocytes from the AIR donor were enriched for SOCS3 [22], SLPI [23], and CH25H [24], genes that have all been previously found to be expressed in astrocytes responding to CNS injury.
Title Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations
Authors Andrew P Voigt et al.
Date 2020.2
Data available GSE142449