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ID 3500
Class Mammalia
Species Homo sapiens
Tissue Lymph node
Sample Tissue
Disease type Influenza vaccination
Cell type B cells
Cell type (subtype) PBs
Cell marker CD79A, CD19, MS4A1, JCHAIN, XBP1, PRDM1, IRF4, SEC11C, FKBP11
Frequency
PubMed ID 32866963
Journal Nature
SCI IF 49.962
Evidence BCL6, RGS13, MEF2B, STMN1, ELL3, and SERPINA9 for GC B cells; XBP1, IRF4, SEC11C, FKBP11, JCHAIN, and PRDM1 for PBs; TCL1A, IL4R, CCR7, IGHM, and IGHD for na_ve B cells; TBX21, FCRL5, ITGAX, NKG7, ZEB2, and the lack of CR2 for activated B cells (ABCs); and TNFRSF13B, CD27, and CD24 for resting memory B (RMB) cells.
Title Human germinal centres engage memory and naive B cells after influenza vaccination
Authors Jackson S Turner et al.
Date 2020.1
Data available GSE148633