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ID 3494
Class Mammalia
Species Homo sapiens
Tissue Lymph node
Sample Tissue
Disease type Normal
Cell type Endothelial cells
Cell type (subtype) Lymphatic endothelial cells (LECs)
Cell marker ACKR4
Frequency
PubMed ID 32426372
Journal Front Cardiovasc Med
SCI IF 3.917
Evidence Subset-specific markers with functional implications include the atypical chemokine receptor ACKR4 (also known as CCRL1), specifically expressed by the LEC layer that forms the ceiling (cLECs) of the subcapsular sinus (SCS) (9), where lymph enters from the afferent collecting vessels.
Title A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature
Authors Menglan Xiang et al.
Date 2020.4
Data available GSE143877, GSE145121