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ID 3734
Class Mammalia
Species Homo sapiens
Tissue Neuruloids
Sample Organoids
Disease type Normal
Cell type Epithelial cells
Cell type (subtype) NE1
Cell marker PAX3, EMX2, EMX1, BARHL1, LHX5
Frequency
PubMed ID 31501559
Journal Nat Biotechnol
SCI IF 36.558
Evidence Two adjacent groups were of neuroepithelial (NE) identity (NE1 and NE2), and one displayed a signature of early neurons (Fig. 3c). These populations had a dorsal identity, demonstrated by expression of PAX3 and lack of SHH and NKX2.1.
Title Self-organizing neuruloids model developmental aspects of Huntington disease in the ectodermal compartment
Authors Tomomi Haremaki et al.
Date 2019.1
Data available GSE118682