Search | Result
ID | 3734 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Neuruloids |
Sample | Organoids |
Disease type | Normal |
Cell type | Epithelial cells |
Cell type (subtype) | NE1 |
Cell marker | PAX3, EMX2, EMX1, BARHL1, LHX5 |
Frequency | |
PubMed ID | 31501559 |
Journal | Nat Biotechnol |
SCI IF | 36.558 |
Evidence | Two adjacent groups were of neuroepithelial (NE) identity (NE1 and NE2), and one displayed a signature of early neurons (Fig. 3c). These populations had a dorsal identity, demonstrated by expression of PAX3 and lack of SHH and NKX2.1. |
Title | Self-organizing neuruloids model developmental aspects of Huntington disease in the ectodermal compartment |
Authors | Tomomi Haremaki et al. |
Date | 2019.1 |
Data available | GSE118682 |