Search | Result
| ID | 3217 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Lung |
| Sample | Tissue |
| Disease type | NA |
| Cell type | Fibroblasts |
| Cell type (subtype) | Cluster 2 |
| Cell marker | Itga8, Col1a1, Pdgfra, Tcf21 |
| Frequency | |
| PubMed ID | 29999500 |
| Journal | J Clin Invest |
| SCI IF | 11.864 |
| Evidence | based on common expression of fibroblast markers, such as Col1a1, Pdgfra, and Tcf21 (Supplemental Figure 2C), but they were segregated by markers that were anatomically distinct. Flow cytometry analysis demonstrated that cluster 1 markers Ly6a and Ly6c1 were enriched in the GLI1+ fraction of the GLI2+ mesenchyme |
| Title | Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype |
| Authors | Peng et al. |
| Date | 2018.1 |
| Data available | NA |
