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ID 3486
Class Mammalia
Species Homo sapiens
Tissue Lymph node
Sample Tissue
Disease type Normal
Cell type Endothelial cells
Cell type (subtype) Lymphatic endothelial cells (LECs)
Cell marker CD31, PDPN, PROX1
Frequency
PubMed ID 31402260
Journal Immunity
SCI IF 31.745
Evidence CCL20, CXCL5, and CXCL1 were abundantly ex_x0002_pressed in cluster 2 (LEC II) (Figure 1D). We also found that LEC II (cluster 2) and LEC VI (cluster 6) had shared gene expression signatures, including DARC and CXCL1 (Figures 1D and S2A), although LEC II (cluster 2) selectively expressed TNFRSF9 (also known as CD137), CCL20, and CXCL5, and LEC VI (cluster 6) specifically expressed multiple C-type lectins such as CLEC4G, CLEC4M, and CD209
Title Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial cells Heterogeneity and Mechanisms of Homing for Neutrophils
Authors Akira Takeda et al.
Date 2019.9
Data available GSE124494