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ID 3079
Class Mammalia
Species Homo sapiens
Tissue Liver
Sample NA
Disease type Primary and relapsed hepatocellular carcinoma
Cell type Natural killer (NK) cells
Cell type (subtype) NK CD16
Cell marker GNLY, GZMB, KLRD1, KLRF1, PRF1, HAVCR2, KIR2DL-1, KIR2DL-3
Frequency
PubMed ID 33357445
Journal CELL
SCI IF 38.63
Evidence NK CD16 (FCGR3A) cells overexpressed cytotoxic genes, including GNLY, GZMB, and PRF1, the inhibitory-related gene HAVCR2 (Al Omar et al., 2011) (Figure 3C), and inhibitory KIRs (KIR2DL-1 and KIR2DL-3) (Figure S3B). The high expression of FCGR3A suggested that these cells may be recruited from the peripheral blood
Title Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma
Authors Sun et al.
Date 2021.1
Data available NA