ID |
3079 |
Class |
Mammalia |
Species |
Homo sapiens |
Tissue |
Liver |
Sample |
NA |
Disease type |
Primary and relapsed hepatocellular carcinoma |
Cell type |
Natural killer (NK) cells |
Cell type (subtype) |
NK CD16 |
Cell marker |
GNLY, GZMB, KLRD1, KLRF1, PRF1, HAVCR2, KIR2DL-1, KIR2DL-3 |
Frequency |
|
PubMed ID |
33357445
|
Journal |
CELL |
SCI IF |
38.63 |
Evidence |
NK CD16 (FCGR3A) cells overexpressed cytotoxic genes, including GNLY, GZMB, and PRF1, the inhibitory-related gene HAVCR2 (Al Omar et al., 2011) (Figure 3C), and inhibitory KIRs (KIR2DL-1 and KIR2DL-3) (Figure S3B). The high expression of FCGR3A suggested that these cells may be recruited from the peripheral blood |
Title |
Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma |
Authors |
Sun et al. |
Date |
2021.1 |
Data available |
NA |