Search | Result
| ID | 3031 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Liver |
| Sample | NA |
| Disease type | Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA) |
| Cell type | CD8 T cells |
| Cell type (subtype) | CD8 cytotoxicity T cells |
| Cell marker | CD8, GZMA, GZMB, PRF1, GZMH |
| Frequency | |
| PubMed ID | 31588021 |
| Journal | Cancer Cell |
| SCI IF | 26.602 |
| Evidence | Some of these subtypes could be identified as CD4+ , CD8+ , and regulatory T cells (Tregs) based on known lineage-specific marker genes, we found that T cell cytotoxicity-related genes (e.g., GZMA, GZMB, GZMH, and PRF1) were highly ex_x0002_pressed in both CD8+ and CD4+ T cells derived from Div-Low tumors in comparison with those from Div-High tumors |
| Title | Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer |
| Authors | Lichun Ma et al. |
| Date | 2019.1 |
| Data available | GSE125449 |
