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ID 2955
Class Mammalia
Species Homo sapiens
Tissue Liver
Sample Tissue
Disease type De novo autoimmune hepatitis
Cell type Myeloid cells
Cell type (subtype) Monocytes/macrophages
Cell marker HMGB1, CARD19, TIMP1
Frequency
PubMed ID 30072988
Journal Front Immunol
SCI IF 5.085
Evidence Feature plots showing signifcant overexpression of HMGB1 (p = 2.62 × 10_69, fold > 3), CARD19 (p = 2.13 × 10_59, fold > 2), and TIMP1 (p = 1.03 × 10_79, fold > 3) in clusters 3 + 4 compared to cluster 6 i.e., signifcant overexpression in monocytes/macrophages of subjects with DAIH compared to monocytes/macrophages of LTC subjects.
Title Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis
Authors Adam S Arterbery et al.
Date 2018.7
Data available NA