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ID 2948
Class Mammalia
Species Homo sapiens
Tissue Liver
Sample NA
Disease type Fibrolamellar carcinoma
Cell type Tumor cells
Cell type (subtype) Malignant and proliferative tumor cell
Cell marker EPCAM, KRT, CPS1, CD68
Frequency
PubMed ID 31669305
Journal Am J Pathol
SCI IF 3.491
Evidence Multiple FLC marker genes were also most abundant in these two largest clusters, including HepPar1 (carbamoyl phosphate synthase1, CPS1), EPCAM, Cytokeratins (KRT) , and CD68 (Fig 2C). The presence of these markers identifies these cells as the epithelial, and presumed malignant, proliferative tumor cells.
Title Single cell RNA sequencing identifies YAP1-dependent hepatic mesothelial progenitors in fibrolamellar carcinoma
Authors Mark L et al.
Date 2020.1
Data available NA