ID |
2860 |
Class |
Mammalia |
Species |
Homo sapiens |
Tissue |
Kidney |
Sample |
Tissue |
Disease type |
Tumor-nephrectomy, allograft kidney transplant surveillance, preperfusion transplant biopsy samples |
Cell type |
Muscle cells |
Cell type (subtype) |
Vascular smooth muscle cells |
Cell marker |
ACTA2, TAGLN, ITGA8, SYNPO2 |
Frequency |
|
PubMed ID |
32107344
|
Journal |
JCI Insight |
SCI IF |
6.205 |
Evidence |
Figure 3B indicates the cluster (or cell type) specificity of the most differentially expressed genes in each cluster.Cluster 9 contained cells with known markers of smooth muscle cells, _CTA2, and_AGLN, consistent with vascular smooth muscle cells and mesangial cells (VSMC/MC). The specific antibody staining of ITGA8 and SYNPO2 in the HPA authenticated the presence of MCs in this cluster |
Title |
Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker |
Authors |
Rajasree Menon et al. |
Date |
2020.3 |
Data available |
GSE140989 |