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ID 2860
Class Mammalia
Species Homo sapiens
Tissue Kidney
Sample Tissue
Disease type Tumor-nephrectomy, allograft kidney transplant surveillance, preperfusion transplant biopsy samples
Cell type Muscle cells
Cell type (subtype) Vascular smooth muscle cells
Cell marker ACTA2, TAGLN, ITGA8, SYNPO2
Frequency
PubMed ID 32107344
Journal JCI Insight
SCI IF 6.205
Evidence Figure 3B indicates the cluster (or cell type) specificity of the most differentially expressed genes in each cluster.Cluster 9 contained cells with known markers of smooth muscle cells, _CTA2, and_AGLN, consistent with vascular smooth muscle cells and mesangial cells (VSMC/MC). The specific antibody staining of ITGA8 and SYNPO2 in the HPA authenticated the presence of MCs in this cluster
Title Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker
Authors Rajasree Menon et al.
Date 2020.3
Data available GSE140989