Search | Result
ID | 2848 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Kidney |
Sample | Organoids |
Disease type | Normal |
Cell type | Nephron |
Cell type (subtype) | Nephron progenitors |
Cell marker | CITED1, SIX1, SIX2, LYPD1, DAPL1 |
Frequency | |
PubMed ID | 30846463 |
Journal | Development |
SCI IF | 5.611 |
Evidence | Cluster 2 showed expressionof the nephron progenitor markers SIX1, SIX2 and CITED1, as wellas the stromal marker PAX3 that has previously been associated withmyogenic Wilms' tumours.Cluster 0 (430 cells), the largestcluster, showed a more committed nephron progenitor signature, with expression of early renal vesicle markers PAX2, PAX8, LHX1and JAG1 as well as the Human NP markers LYPD1 and DAPL1. |
Title | Kidney micro-organoids in suspension culture as a scalable source of Human pluripotent stem cell-derived kidney cells |
Authors | Santhosh V Kumar et al. |
Date | 2019.3 |
Data available | GSE117211, GSE108291 |