Search | Result
| ID | 2847 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Kidney |
| Sample | Organoids |
| Disease type | Normal |
| Cell type | Nephron |
| Cell type (subtype) | Nephron progenitors |
| Cell marker | SIX1, WT1, LHX1, PAX2, EYA1, OSR1 |
| Frequency | |
| PubMed ID | 30846463 |
| Journal | Development |
| SCI IF | 5.611 |
| Evidence | Immunofluorescence for the IM/nephron progenitor/nephron marker PAX2 was clearly higher in day 7+11 kidney micro-organoids exposed to 1_M CHIR99021 (Fig.1D), with qPCR performed on the day 7 monolayer cultures showing increased expression of key IM/nephron progenitor markers (PAX2, _T1, _HX1, _SR1, _IX1, _YA1) as well as_NT11_nd_ATA3, which are expressed in the ureteric tip and collecting duct but are not unique to these sites (Fig.1E) |
| Title | Kidney micro-organoids in suspension culture as a scalable source of Human pluripotent stem cell-derived kidney cells |
| Authors | Santhosh V Kumar et al. |
| Date | 2019.3 |
| Data available | GSE117211, GSE108291 |
