Search | Result
| ID | 8849 |
|---|---|
| Class | Mammalia |
| Species | Mouse |
| Tissue | Splenocytes |
| Sample | Tissue |
| Disease type | CHIKV-infected |
| Cell type | T cells |
| Cell type (subtype) | T cells |
| Cell marker | CD3e |
| Frequency | |
| PubMed ID | 32699843 |
| Journal | Cell Rep Med |
| SCI IF | NA |
| Evidence | immune cell subsets were identified by their celltype-specific gene expression:CD3e (T cells), Ncr1 (NK cells), CD79a (B cells), Flt3 (DCs), Sdc1 (plasmablasts), Adgre1 (macro phages), S100a8 (neutrophils), and Ccr2/Ly6c2 (monocytes);Among activated T cells, the fre quency of cycling CD8+ T cells, characterized by the expression of Ccnb2, Ccna2, Cdca3, and Mki67 (Figure S3A), was increased in anti-CD137 mAb-treated Mouse compared to isotype control mAb-treated animals at 7 dpi |
| Title | An Agonistic Anti-CD137 Antibody Disrupts Lymphoid Follicle Structure and T-Cell-Dependent Antibody Responses |
| Authors | Jun P. Hong et al. |
| Date | 2020.6 |
| Data available | GSE141111, GSE141117 |
