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ID 4503
Class Mammalia
Species Homo sapiens
Tissue Testicle
Sample Tissue
Disease type Normal
Cell type Muscle cells
Cell type (subtype) Smooth muscle cells
Cell marker NOTCH3
Frequency
PubMed ID 31928944
Journal Cell Stem Cell
SCI IF 13.19
Evidence Clusters 1_3 are germ cells, with C1 representing spermatogonia (UTF1+, FGFR3+), C2 consisting of spermatocytes (SYCP3+), and C3 identifying post-meiotic spermatids (PRM3+). Clusters 4_8 correspond to a heterogenous mixture of Sertoli cells (C4; SOX9+), Leydig and myoid-like cells (C5; IGF1+ and/or ACTA2+), smooth muscle (C6; NOTCH3+), macrophages (C7 CD14+), and Endothelial cellss (C8; VWF+), respectively (see Figures S1D and S1E for additional markers).
Title The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty
Authors Jingtao Guo et al.
Date 2020.2
Data available GSE134144