Search | Result
| ID | 2423 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Heart |
| Sample | Tissue |
| Disease type | Hypoplastic Left Heart Syndrome |
| Cell type | Endothelial cells |
| Cell type (subtype) | Lymphatic endothelium |
| Cell marker | CDH5, LYVE1 |
| Frequency | |
| PubMed ID | 32810435 |
| Journal | Cell Stem Cell |
| SCI IF | 20.86 |
| Evidence | The majority of the cell typesexpected to be present in the heart were successfully retrievedby scRNA-seq analysis as shown in the UMAP projection, including a certain amount of CMs (TNNI3+) in addition to panECs (CDH5+) (Figures 1B and 1C). Of note, CDH5+ populationsclustered into three subgroups endocardium (NPR3+), endothelium (APLN+) (unless specified, endothelium refers to thevascular endothelium), and lymphatic endothelium (LYVE1+)(Figure 1C). |
| Title | Intrinsic Endocardial Defects Contribute to Hypoplastic Left Heart Syndrome |
| Authors | Yifei Miao et al. |
| Date | 2020.1 |
| Data available | GSE138979 |
