| ID |
2284 |
| Class |
Mammalia |
| Species |
Homo sapiens |
| Tissue |
Gut |
| Sample |
Organoids |
| Disease type |
Childhood Crohn's Disease |
| Cell type |
Epithelial cells |
| Cell type (subtype) |
Epithelial progenitors |
| Cell marker |
MKI67, LGR5, BEX5, TACSTD2 |
| Frequency |
|
| PubMed ID |
33290721
|
| Journal |
Dev Cell |
| SCI IF |
10.092 |
| Evidence |
We used BEX5 as a marker of uniform progenitors alongside LGR5 and MKI67 to visualize epithelial changes during villus emergence. In addition, we included TACSTD2 (Trop2A in Mouse), which has been shown to mark the murine fetal intestinal progenitors |
| Title |
Single-Cell Sequencing of Developing Human Gut Reveals Transcriptional Links to Childhood Crohn Disease |
| Authors |
Rasa Elmentaite et al. |
| Date |
2020.12 |
| Data available |
NA |
