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ID 2147
Class Mammalia
Species Homo sapiens
Tissue Endocardial cells
Sample Cell line
Disease type Normal
Cell type Endothelial cells
Cell type (subtype) Endothelial cells
Cell marker PECAM1, CDH5, KDR, ENG, SOX17, SOX18, NOTCH4, KLF2, ETS
Frequency
PubMed ID 31028265
Journal Nat Commun
SCI IF 12.121
Evidence One third of cells (1105) (cluster1) were CDH5+ including endoglin (ENG+) cells (849), PECAM1+ cells (729), KLF2+ cells(161) as well as NOTCH4+ (1005) cells, pointing to an endothelial and endocardial cell population
Title Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis
Authors Tui Neri et al.
Date 2019.4
Data available GSE73546