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ID 200
Class Aves
Species Chicken
Tissue Gonad
Sample Tissue
Disease type Normal
Cell type Granulosa cells
Cell type (subtype) Pre-granulosa cells
Cell marker Foxl2, Cyp19A1, Fgfr3
Frequency
PubMed ID 32268081
Journal Cell Rep
SCI IF 9.423
Evidence Cluster 1 corresponded to an Endothelial cells population present in both sexes (highly expressing SOX18 and CDH5), whereas c2 were (coelomic) epithelial cells expressing keratins(e.g., KRT7 and KRT18) and PITX2. Cluster 4 was an interstitialcell population, with enriched expression of mesenchymal markers as well as extracellular matrix-related transcripts (COL3A1, COL1A2, POSTN, DCN, and ACTA2)
Title Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo
Authors Martin Andres Estermann et al.
Date 2020.4
Data available NA