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ID 2066
Class Mammalia
Species Homo sapiens
Tissue Embryonic stem cells
Sample Organoids
Disease type NA
Cell type Cluster1
Cell type (subtype) Cluster1
Cell marker CTIP2, FEZF2, L1CAM, NRN1
Frequency
PubMed ID 30886407
Journal Nature Neuroscience
SCI IF 20.071
Evidence Cell-type and maturity markers revealed a distinct population of deep-layer subcortical projection neurons (C1, for example, CTIP2, FEZF2) / Genes associated with axon outgrowth/tract formation (L1CAM, NRN1) were expressed more abundantly and at increased levels in the C1_ C2 clusters formed by extra- and intracerebral-projection neurons and to a lesser extent in the C4 population.
Title Cerebral organoids at the air_liquid interface generate diverse nerve tracts with functional output
Authors Giandomenico SL et al.
Date 2019.3
Data available GSE124174