| Evidence |
The clustering result was annotated by the known markers including KRT12, KRT3 and GJA1 for differentiated cell; KRT14, KRT15 and KRT19 for progenitor; MKI67, BIRC5 and RRM2 for amplifying cell; TCF4, POSTN and A2M for LSC; TYR, TYRP1 and MLANA for melanocyte; and KRT4, KRT7 and KRT13 for conjunctival cells (Fig. 2F).In contrast, the expression levels of KRT3, SPRR2A, SPRR1B and IVL by C1/ 3/4 were significantly lower than that of C0/2, suggesting that C1/3/4 represent post-mitotic cells (PMCs), an early stage of differentiated cells |
