Search | Result
| ID | 1960 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Colon |
| Sample | Tissue |
| Disease type | Normal |
| Cell type | CD4 T cells |
| Cell type (subtype) | Follicular helper cells |
| Cell marker | ICOS, CXCR5 |
| Frequency | |
| PubMed ID | 32066951 |
| Journal | Nat Immunol |
| SCI IF | 20.479 |
| Evidence | CD4+ T cells were typically CXCR5+, ICOShi follicular helper cells, and SELL+ (encodes CD62L), CCR7+ central memory cells (Figure 2b, c). In contrast, colonic CD4+ T cells had a more effector phenotype, expressing high levels of the tissue residency marker CD69 17, falling into the TH17 (CCR6+, IL22+, CCL20+) or TH1 (CXCR3+, IFNG+) subtypes. |
| Title | Distinct microbial and immune niches of the Human colon |
| Authors | James et al. |
| Date | 2020.3 |
| Data available | gutcellatlas.org |
