Search | Result
| ID | 2851 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Kidney |
| Sample | Organoids |
| Disease type | Autosomal recessive polycystic kidney disease |
| Cell type | Nephron |
| Cell type (subtype) | Nephron progenitors |
| Cell marker | CITED1, SIX1, SIX2, WT1, TMEM100, ITGA8, EYA1, SALL1, ECEL1 |
| Frequency | |
| PubMed ID | 31303547 |
| Journal | Cell Stem Cell |
| SCI IF | 20.86 |
| Evidence | These transient, PTA-like structures not only expressed NPC markers (SIX2 and SALL1) but also acquired LHX1 and PAX8 expression, indicating the initiation of nephrogenesis.Figure 2B.FACS analysis of NPC (SIX1, SALL1) and vascular endothelial (CD31) markers in the secondtrimester Human fetal kidneys.Figure S2D |
| Title | Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network |
| Authors | Jian Hui Low et al. |
| Date | 2019.9 |
| Data available | GSE132026 |
