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ID 1733
Class Mammalia
Species Homo sapiens
Tissue Breast
Sample Tissue
Disease type Breast cancer
Cell type CD4 T cells
Cell type (subtype) CD4 IL-7R
Cell marker IL7R, CD40LG, JUN, CD69, DUSP1, FOS, PLAC8
Frequency
PubMed ID 29942092
Journal Nature medicine
SCI IF 36.13
Evidence We identified ten unique clusters based on their gene expression profiles (Fig. 2c). This included three distinct CD8A+ T cell clusters and four distinct CD4+ T cell clusters, including a Treg (FOXP3+CTLA-4+) and a follicular CD4+CXCL13+ cell cluster8.
Title Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis
Authors Savas et al.,
Date 2018.7
Data available GSE110686