Search | Result
| ID | 1725 |
|---|---|
| Class | Mammalia |
| Species | Homo sapiens |
| Tissue | Breast |
| Sample | Tissue |
| Disease type | TNBC (triple-negative breast cancer) |
| Cell type | Mesenchymal cells |
| Cell type (subtype) | Mesenchymal cells |
| Cell marker | VIM, ITGB1, LAMC2 |
| Frequency | |
| PubMed ID | 29091754 |
| Journal | Cell Rep |
| SCI IF | 9.423 |
| Evidence | These included the following a mesenchymal/ stem (M/S) cluster (salmon color), which had significantly elevated expression of EGFR and elevated expression of genes associated with mesenchymal (VIM, ITGB1, and LAMC2) and stem cell-like (ITGA6 and ITGB4) states as well as hypoxia-induced transcripts (ANGPTL4, ADM, and PLAU) |
| Title | A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer. |
| Authors | Paul Savage et al. |
| Date | 2017.1 |
| Data available | PRJNA374893, PRJNA39283 |
