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ID 1711
Class Mammalia
Species Homo sapiens
Tissue Breast
Sample Cell line
Disease type Triple-Negative Breast Cancer
Cell type Bbdi-resistant cells
Cell type (subtype) Bbdi-resistant cells
Cell marker CDK4, CCND1, BCL2L1
Frequency
PubMed ID 32416067
Journal Molecular Cell
SCI IF 15.584
Evidence Similarly, BBDI-resistant and parental cells separated very clearly, and BBDI-resistant cell cluster-specific genes included several CRISPR screen hits, such as CDK4, CCND1, and BCL2L1 (Figures 7A and S7A).
Title Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
Authors Shaokun Shu et al.
Date 2020.6
Data available GSE131102