Search | Result
ID | 1664 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Brain |
Sample | Organoids |
Disease type | Multiple sclerosis |
Cell type | CD8 T cells |
Cell type (subtype) | Memory CD8 T cells |
Cell marker | NKG7, GZMK, GZMA, CCL5, CCL4, PDCD1, CD69, GZMM, LGALS1, CXCR6, LGALS3, PRDM1 |
Frequency | |
PubMed ID | 32948672 |
Journal | Sci Immunol |
SCI IF | 13.423 |
Evidence | Last, the CSF contained a cluster of memory CD8 T cells (CD8 memory CSF) that was marked by cytotoxic genes (CCL5, NKG7, GZMK, GZMA, GZMM, and CCL4) and genes related to tissue residence [CD69, LGALS1, LGALS3 (24, 34, 36), PDCD1, PRDM1 (41, 42), and CXCR6. |
Title | Transcriptomic and clonal characterization of T cells in the Human central nervous system |
Authors | Jenna L Pappalardo et al. |
Date | 2020.9 |
Data available | phs002222.v1.p1, GSE157277, GSE155488 |