| Evidence |
These clusters display significant enrichment for Endothelial cells-specific gene signatures (Fig. 2c) 20, 22, and several neuroepithelial markers (VIM and HES1) 23 which also act as vascular remodelers (Supplementary Fig. 3c). Analysis of cells within EN cluster revealed that vhCOs showed dramatic expression of several vasculogenesis factors (FLT1, HAND1, MME, and VTN), pericyte markers (PDGRFbeta and THY1), collagens and cell adhesion-related genes; control hCOs lacked the expression of these markers |
