Search | Result
ID | 1431 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Brain |
Sample | Organoids |
Disease type | Healty |
Cell type | Progenitor cells |
Cell type (subtype) | Dorsal forebrain progenitors |
Cell marker | PAX6, EMX1 |
Frequency | |
PubMed ID | 31168097 |
Journal | Nature |
SCI IF | 49.962 |
Evidence | Immunohistochemistry (IHC) for the dorsal forebrain progenitor markers EMX1 and PAX6 and for the early pan-neuronal marker MAP2 confirmed the presence of rosette-like structures at one month, when dorsalized progenitors lined ventricle-like cavities. The cortical pyramidal neuron subtype markers CTIP2 and SATB2 were expressed by 3 months and subsequently maintained |
Title | Individual brain organoids reproducibly form cell diversity of the Human cerebral cortex. |
Authors | Velasco S et al. |
Date | 2019.6 |
Data available | GSE129519 |