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ID 1431
Class Mammalia
Species Homo sapiens
Tissue Brain
Sample Organoids
Disease type Healty
Cell type Progenitor cells
Cell type (subtype) Dorsal forebrain progenitors
Cell marker PAX6, EMX1
Frequency
PubMed ID 31168097
Journal Nature
SCI IF 49.962
Evidence Immunohistochemistry (IHC) for the dorsal forebrain progenitor markers EMX1 and PAX6 and for the early pan-neuronal marker MAP2 confirmed the presence of rosette-like structures at one month, when dorsalized progenitors lined ventricle-like cavities. The cortical pyramidal neuron subtype markers CTIP2 and SATB2 were expressed by 3 months and subsequently maintained
Title Individual brain organoids reproducibly form cell diversity of the Human cerebral cortex.
Authors Velasco S et al.
Date 2019.6
Data available GSE129519