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ID 1378
Class Mammalia
Species Homo sapiens
Tissue Brain
Sample Organoids
Disease type Normal
Cell type Ganglion cells
Cell type (subtype) Retinal ganglion cells
Cell marker NEFL, NEFM, PCP4
Frequency
PubMed ID 32051547
Journal Molecular Psychiatry
SCI IF 12.384
Evidence clusters were classifified to reveal the presence of DKK3+ SOX9+ Müller glia (cluster 0 and 11), GFAP+ astrocytes (cluster 1), NRL+ RCVRN+ CRX+ GBN3+ GNGT1+, TULIP1++ neurons (cluster 2, 9, and 13), HES1+ GLUL+ astrocytes (cluster 3 and 6), VIM+ VCAN+ KLF4+ neuroepithelial cells (cluster 4 and 8), GFAP+ SOX2+ NFIB+ glial intermediate cells (cluster 5), AGT+ astrocytes (cluster 7), MAP2+ DCX+ neurons (cluster 10), PAX6+ SOX2+ radial glial cells (cluster 12), PCP4+ NEFL+ NEFM+ retinal ganglion cells (cluster 14), TOP2A+ GLI3+ PAX6+ SOX2+ proliferative neural progenitor cells (cluster 15).
Title Glial cell diversity and methamphetamine-induced neuroinflflammation in Human cerebral organoids
Authors Jason Dang et al.
Date 2020.2
Data available NA