Search | Result
ID | 1364 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Brain |
Sample | Organoids |
Disease type | NOD/scid/IL2rg (NSG) |
Cell type | Pericytes |
Cell type (subtype) | Pericytes |
Cell marker | RGS5, KCNJ8, PDGFRB, ABCC9, CSPG4, CD248, FOXF2, HIGD1B, FOXC1, CD19, RBFOX1, GFAP, ANPEP, PTN |
Frequency | |
PubMed ID | 32961131 |
Journal | Cell |
SCI IF | 38.653 |
Evidence | Figure 5C. Pericytes are identified by PDGFRB, CD248, RGS5, and FOXF2 expression and specifically express CD19. Figure 1F. Figure 4D. We observed that these cells showed strong enrichment of reported pericyte markers, such as ABCC9 and KCNJ8, without enrichment of ACTA2 or other vSMC marker genes, suggesting that they represented bona-fide pericytes. |
Title | Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies |
Authors | Kevin R Parker et al. |
Date | 2020.1 |
Data available | GSE153647 |