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ID 1364
Class Mammalia
Species Homo sapiens
Tissue Brain
Sample Organoids
Disease type NOD/scid/IL2rg (NSG)
Cell type Pericytes
Cell type (subtype) Pericytes
Cell marker RGS5, KCNJ8, PDGFRB, ABCC9, CSPG4, CD248, FOXF2, HIGD1B, FOXC1, CD19, RBFOX1, GFAP, ANPEP, PTN
Frequency
PubMed ID 32961131
Journal Cell
SCI IF 38.653
Evidence Figure 5C. Pericytes are identified by PDGFRB, CD248, RGS5, and FOXF2 expression and specifically express CD19. Figure 1F. Figure 4D. We observed that these cells showed strong enrichment of reported pericyte markers, such as ABCC9 and KCNJ8, without enrichment of ACTA2 or other vSMC marker genes, suggesting that they represented bona-fide pericytes.
Title Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies
Authors Kevin R Parker et al.
Date 2020.1
Data available GSE153647