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ID 1331
Class Mammalia
Species Homo sapiens
Tissue Brain
Sample Cell line
Disease type HIV-associated neurocognitive disorders
Cell type Iast
Cell type (subtype) Iast
Cell marker THBS1, SOX9
Frequency
PubMed ID 32220329
Journal Stem Cell Reports
SCI IF 6.032
Evidence We assigned clusters to one of the three cell types by expression of several key genes:iMg by expression of IBA1, PU.1, and CD4; iNrn by expression of MAP2 and SYN1; and iAst by expression of THBS1 and SOX9 (Figures 4C_6E).
Title Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection
Authors Sean K Ryan et al.
Date 2020.4
Data available GSE143686