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ID 1292
Class Mammalia
Species Homo sapiens
Tissue Blood
Sample NA
Disease type HPV, head and neck cancer, normal
Cell type B cells
Cell type (subtype) Germinal centre B cells
Cell marker MS4A1, TCL1A, AICDA, MME, ID3
Frequency
PubMed ID 33208941
Journal Nature
SCI IF 49.962
Evidence The ABC and GCB clusters were characterized by the expression of MS4A1 (encoding CD20) and ID3, with GPR183 (EBI2) being absent in GCBs, consistent with its role in mediating egress from germinal centres22 (Extended Data Fig.5c). The ASC cluster was characterized by the expression of CD38, MZB1, PRDM1 (encoding BLIMP-1) and XBP1, whereas GCBs expressed TCL1A, AICDA and MME (CD10).
Title Defining HPV-specific B cell responses in patients with head and neck cancer
Authors Andreas Wieland et al.
Date 2020.11
Data available GSE153559