Search | Result
ID | 1292 |
---|---|
Class | Mammalia |
Species | Homo sapiens |
Tissue | Blood |
Sample | NA |
Disease type | HPV, head and neck cancer, normal |
Cell type | B cells |
Cell type (subtype) | Germinal centre B cells |
Cell marker | MS4A1, TCL1A, AICDA, MME, ID3 |
Frequency | |
PubMed ID | 33208941 |
Journal | Nature |
SCI IF | 49.962 |
Evidence | The ABC and GCB clusters were characterized by the expression of MS4A1 (encoding CD20) and ID3, with GPR183 (EBI2) being absent in GCBs, consistent with its role in mediating egress from germinal centres22 (Extended Data Fig.5c). The ASC cluster was characterized by the expression of CD38, MZB1, PRDM1 (encoding BLIMP-1) and XBP1, whereas GCBs expressed TCL1A, AICDA and MME (CD10). |
Title | Defining HPV-specific B cell responses in patients with head and neck cancer |
Authors | Andreas Wieland et al. |
Date | 2020.11 |
Data available | GSE153559 |